Automated screening method for the Wassermann reaction.

Automated screening method for the Wassermann reaction.

For a number of years we have considered the Wassermann reaction to be eminently suitable for complete automation. It was after our experience with the Technicon Autoanalyser doing chemical analyses that we decided to experiment with the Wassermann reaction. The following paper records the details of our method, based on the Whitechapel technique (Wilkinson, 1962). It does not include details o...

Large-scale screening by the automated Wassermann reaction.

In view of the drawbacks in the use of the Kahn test for large-scale screening of blood donors, mainly those of human error through work overload and fatiguability, an attempt was made to adapt an existing automated complement-fixation technique for this purpose. This paper reports the successful results of that adaptation.

Concerning the Wassermann Reaction

tionally collected and kept for some time, is a very poor control. Some positive sera give a complete fixation of the usual one or more MHD of the complement in a 1 in 200 dilution; others can do so in 1 in 5 dilution only. The margin.of variation allowed for in this control, 5 to 200, is too wide to be useful in indicating whether the antigen-antibody systems involved in the reaction of comple...

Wassermann Reaction

Concerning the Wassermann Reaction

Sir,?In the December 1943 issue of the Indian Medical Gazette under the article on ' Concerning the ?Wassermann Reaction' I fail to see why smallpox vaccination as one of the causes producing false positive reactions has not been mentioned. Hence will you please publish the following in your valuable monthly :? False positive syphilitic reactions have been attributed to numerous causes, with sm...